How to Apply - FRONTLINE® Plus

Sharpen your flea and tick killing skills with tips and a slide show demonstration.

Sharpen your flea and tick killing skills with helpful tips.

You may not have a sword or ninja stars, but you do have a powerful weapon that starts killing after 1 easy application.

You may not have ninja stars, but you do have a powerful weapon that starts killing after 1 easy application.

To get started, remove the applicator from the package, hold the foil upward, then snap off the tip. You'll find it's designed to easily dispense the liquid solution onto the skin between your pet's shoulder blades. Just view the slide show at the right and read the instructions below—and you'll be killing in no time.

To get started, view the slide show at the right and read the instructions below—and you'll be killing in no time.

You may not have a sword or ninja stars, but you do have a powerful weapon that starts killing after 1 easy application. For instructions, see below.

Follow these instructions.

To apply, view the slide show demonstration–and reapply every 30 days.

Follow these instructions.

To apply, simply follow these instructions–and repeat every 30 days:

Remove Applicator: Lift and remove the plastic tab to expose foil backing. Then peel away the foil. Or use scissors to open
Open Applicator: Hold upright with foil side toward you and snap applicator tip
Apply FRONTLINE Plus: Part your pet's hair between the shoulder blades. Place the applicator tip just above the skin and squeeze. Apply entire contents of the applicator in a single spot directly onto the animal's skin. Do not apply on top of the haircoat. Avoid contact with treated area until dry

Here are some additional tips.

Remove the pet's collar
Apply as a spot between your pet's shoulder blades in 1 area that can't be licked
Avoid touching the wet application spot
Wait 24 hours to allow solution to dry before bathing or letting your pet swim
Give each of your pets its own complete dose

The flea life cycle—break it, or else.

Flea infestations start with just 2 fleas laying hundreds of flea eggs within a matter of days.¹ So preventing an infestation involves more than killing just adult fleas.

The 4 Stages of the Flea Life Cycle

Don't forget to reapply every 30 days. Sign up for e-mail reminders.

With FRONTLINE Plus, it's easy to help protect your pet against fleas and ticks. And now, remembering to do so can be easy, too.

See how fast fleas reproduce.

Use this tool to see how fleas can lay eggs and reproduce in just a matter of days.

Find the size that's right for your pet.

Use the selector tool to find the FRONTLINE Plus that's right for your pet. Then speak with your vet.

Mow the grass. Remove the leaves.

Make your yard less appealing to ticks by cutting grass short and eliminating brush piles. See more tips.

Find the size that's right for your pet.

Use the selector tool to find the FRONTLINE Plus that's right for your pet.

1. Dryden M. Biology of fleas of dogs and cats. The Compendium. 1993;15(4):569-578.